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RESEARCH ARTICLE
Year : 2017  |  Volume : 6  |  Issue : 1  |  Page : 77-83

Isolation and identification of cinnamic acid derivatives from the aerial parts of Seidlitzia Rosmarinus Ehrenb. ex Boiss


1 Department of Pharmacognosy, Faculty of Pharmacy, Isfahan University of Medical Sciences,Isfahan, Iran
2 Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Masoud Sadeghi Dinani
Department of Pharmacognosy, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan
Iran
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Source of Support: None, Conflict of Interest: None


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Seidlitzia rosmarinus Ehrenb .ex Boiss. is a woody plant belongs to the Chenopodiaceae family with a vast geographical distribution in Asian countries. As a famous plant in Iran, it is called “Oshnan” in Persian and has been used as a natural soap for many centuries. Despite of vast spread and importance, S. rosmarinus has not been studied phytochemicaly, and this study was conducted to identify the main constituents of the aerial parts of the plant. Phytochemical investigation of S. rosmarinus resulted to the isolation of two cinnamic acid derivatives and a benzaldehyde derivative as the main phenolic compounds of aerial parts of the plant. Using comprehensive spectroscopic methods, including 1D and 2D NMR and MS, chemical structure of the isolated compounds were determined as N-cis-feruloyltyramine (1), N-cis-caffeoyltyramine (2) and p-hydroxyacetophenone (Piceol) (3), respectively. To the best of our knowledge, isolation and identification of these compounds from S. rosmarinus are reported for the first time in this study.


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