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RESEARCH ARTICLE
Year : 2018  |  Volume : 7  |  Issue : 2  |  Page : 221-226

Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes


1 Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
2 Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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Source of Support: None, Conflict of Interest: None


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The air- dried and ground rhizomes of Eremostachys macrophylla Montbr. & Auch., as wild-growing plant in East Azerbaijan province, of Iran, were extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH) solvents using a soxhlet apparatus. The 10% MeOH in water Sep-Pak fractions of the MeOH extract was subjected to preparative reversed- phase high performance liquid chromatography (RP-HPLC) and the isolated pure compounds were identified by one- dimensional nuclear magnetic resonance (1D-NMR) spectroscopic technique. The obtained results showed the presence of two pure components, 6- Hydroxyl Loganin, (1) and Lamalbide (2) with iridoid structures. The results demonstrated the rhizomes of E. macrophylla could be a good source of iridoids.


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