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RESEARCH ARTICLE
Year : 2013  |  Volume : 2  |  Issue : 2  |  Page : 90-97

Essential oil composition of Ferula Assa-Foetida L. fruits from Western Iran


1 Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
3 Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
4 Department of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran
5 School of Biology, Damghan University, Damghan, Iran
6 Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran
7 Novel Drug Delivery Research Center, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, ; Department of Pharmacognosy and Biotechnology, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran

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Chemical composition of the essential oil of the fruit of Ferula assa-foetida L. obtained by steam distillation solvent extraction methodhas been studied by GC/MS for the first time. Fifty-four components, comprising 96.9% of the total oil, were identified.epi-α-Cadinol (23.15 %), germacrene B (10.98 %), α-gurjunene (6.18 %), (Z)-1-propenyl sec-butyl disulfide (5.89 %), 5-epi-7-epi-α-eudesmol (4.89 %), δ-cadinene (4.78 %), γ-cadinene (3.36 %) and germacrene D (3.09 %) were found to be the major constituents of the oil. The oil of the fruit of F. assa-foetida consisted of ten monoterpene hydrocarbons (6.14%), twenty-six sesquiterpene hydrocarbons (43.48%), nine oxygenated sesquiterpenes (37.77%), one oxygenated hydrocarbon (0.35%), and nine volatile sulfides (11.18%).


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