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Year : 2020  |  Volume : 9  |  Issue : 1  |  Page : 136-167

A review on analytical methods of antigout agents

1 Department of Pharmaceutical Chemistry, Amrutvahini College of Pharmacy, Sangamner, Maharashtra, India
2 Department of Pharmaceutical Quality Assurance, Amrutvahini College of Pharmacy, Sangamner, Maharashtra, India

Correspondence Address:
Dr. Ramanlal N Kachave
Department of Pharmaceutical Chemistry, Amrutvahini College of Pharmacy, Sangamner 422608, Maharashtra.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jrptps.JRPTPS_32_19

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The aim of this study was to provide information of the development in analytical perspective of impurity profiling, force degradation, and bioanalysis of pharmaceutical drug substance and drug products used for the treatment of gout. This information was discussed on the basis of year of publication, matrix (active pharmaceutical ingredient, dosage form, and biological fluid), sample preparation technique, column and types of elution in chromatography (isocratic or gradient), detector, and therapeutic categories of drug, which were used for analysis. It focuses mainly on analytical methods including hyphenated techniques for the identification and quantification of impurity, degradants, and metabolites in different pharmaceutical and biological matrices.

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